RESEARCH LAB

Research Studies

Current Johns Hopkins Research Studies

1. CLINICAL TRIAL ON BIPOLAR DEPRESSION:
Dr. Jennifer Payne is conducting a research study to examine the effectiveness of Riluzole in treating the depression phase of bipolar disorder. This outpatient study of medication or placebo will last 9 to 12 weeks. Participants should be between the ages of 18 and 75, have a diagnosis of Bipolar I or Bipolar II, be depressed, and be in current treatment with an outpatient psychiatrist. The study includes medical and psychiatric evaluations as well as time-limited medication treatment at no cost. If you are interested in participating, please contact Annie Chewning at 410-502-2334.

2. CONNECTIONS OF MOOD AND ANXIETY DISORDERS:
Dr. Sean F. MacKinnon is conducting a research study to discover a possible cause of both anxiety and mood symptoms. Anyone who has been part of a Johns Hopkins Genetic study of bipolar disorder is eligible. The study involves a on-time visit to Johns Hopkins Hospital for a session lasting approximately two hours. Study participants will have their breathing and blood pressure measured while they breathe regular air and air mixed with a small amount of carbon dioxide over a period of 15 minutes each (carbon dioxide is a natural byproduct of breathing, and is the gas that makes up soda bubbles). The patterns of response to these tests will be used to look for genes for bipolar and anxiety disorders. If you are interested in participating, or have questions, please call Brandie Craighead at 410-955-3616.

3. EMPLOYMENT AND WORK DISABILITY IN BIPOLAR DISORDER:
Dr. David Schretlen is conducting a study of factors that are associated with work disability and employment in individuals with bipolar disorder. Study participants will be interviewed about their work history and current mood symptoms, and they will take some pencil-and-paper tests of attention, memory, and problem-solving. All reasonably healthy persons with bipolar disorder are welcome to participate, regardless of whether or not they are employed. The assessment will take about 2 and 1/2 hours, and participants will be paid for their time. If you are interested in this study, please call Patricia Gregory at 410-614-4476.

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Sheppard Pratt Research Study:

Sheppard Pratt is seeking volunteers for a clinical research study to evaluate the safety and effectiveness of an approved medicine under investigation for the treatment of depression due to bipolar disorder. To qualify for participation you must:

†Be at least 18 years old
• Have been diagnosed with Bipolar Disorder
• Be experiencing symptoms of depression

As a qualified participant you will receive, at no cost:
• Monitoring of depression and bipolar symptoms
• Study-related examinations
• Study-related medication

If you are experiencing depression due to bipolar disorder please call 410-938-3139 to learn more about becoming a participant in this research study.

American Academy of Child and Adolescent Psychiatry (AACAP)

American Medical Association Publishing Home Page

Dana Foundation

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Internet Mental Health

JHMI-InfoNet: Patient Advocacy Groups

Johns Hopkins Psychiatry Home Page

MEDLINEplus page on Bipolar Disorder

National Alliance for the Mentally Ill (NAMI)

National Alliance for Research on Schizophrenia and Depression (NARSAD)

National Depressive and Manic-Depressive Association (NDMDA)

National Institute of Mental Health (NIMH)

Pendulum's Bipolar Disorder / Manic-Depression Pages

Science Online

Scientific Journals